# Boltz (ChatGPT Plugin)

> Predict structures, screen molecules and proteins, and design binders

- Type: plugin
- Publisher: Boltz (official)
- Categories: Research, Design
- Website: https://chatgpt.com/plugins/Plugin_146eca281b788191ba8a689a3a96f977
- Open in ChatGPT: https://chatgpt.com/plugins/Plugin_146eca281b788191ba8a689a3a96f977
- Version: 0.1.1
- Listed: 2026-10-04

## About

Use Boltz from Codex for biomolecular modeling workflows: predict structure and binding for protein, RNA, DNA, and ligand complexes; rank small-molecule or protein libraries against targets; and design novel small molecules, peptides, antibodies, nanobodies, or custom protein binders with structures and confidence metrics.

## Install

1. **Add it in ChatGPT** Open Plugins in the ChatGPT sidebar (web or desktop), search for “Boltz” and select +. You'll be asked to sign in to any connected service on first use. Then type @ in a chat to call it.

## Skills

- **Boltz Check Status**: Inspect Boltz jobs and recover outputs
- **Boltz CLI Setup**: Install, update, verify, and authenticate boltz-api
- **Boltz Protein Design**: Design peptide or antibody binders
- **Boltz Protein Screen**: Screen protein binders against a target
- **Boltz Small Molecule ADME**: Predict ADME (solubility, permeability, logD) from SMILES
- **Boltz Small Molecule Design**: Design novel ligands for a protein target
- **Boltz Small Molecule Screen**: Screen SMILES libraries against protein targets
- **Boltz Structure and Binding**: Predict complexes and score Boltz binding jobs

## Example prompts

- "Predict EGFR L858R binding to osimertinib"
- "Design nanobodies for a SARS-CoV-2 RBD epitope"
- "Design selective JAK2 binders from Enamine REAL"

## Related

- [Build Web Apps](https://chatgptplugins.directory/plugins/build-web-apps.md): Build frontend-focused web apps with generated assets, browser testing, payments, and...
- [Figma](https://chatgptplugins.directory/plugins/figma.md): Figma design-to-code workflows
- [Adobe](https://chatgptplugins.directory/plugins/adobe.md): Design, combine, and edit
- [Creative Production](https://chatgptplugins.directory/plugins/creative-production.md): Create marketing visuals from a brief or product image.
- [Public Equity Investing](https://chatgptplugins.directory/plugins/public-equity-investing.md): Public equity PM research, long/short, earnings, ETF/index diligence, and memos
- [Product Design](https://chatgptplugins.directory/plugins/product-design.md): Explore and prototype ideas

---
Source: https://chatgptplugins.directory/plugins/boltz · Index: https://chatgptplugins.directory/llms.txt · Independent and community-run. Not affiliated with or endorsed by OpenAI. ChatGPT is a trademark of OpenAI.