Plasmole brings deterministic molecular-biology tools into ChatGPT. Annotate raw DNA (ORF and parts detection), parse GenBank/FASTA files, edit and assemble sequences, design and visualize PCR primers, find restriction sites and predict digests, calculate melting temperature, design CRISPR guides, optimize codons, align two or many sequences, verify a clone against its reference, check a design for problems, export GenBank or FASTA, and fetch public NCBI records by accession, or resolve a gene, plasmid or vector name to one. Plasmid-producing tools render an interactive circular map inline; drag-select a region to design primers against it. Constructs are versioned, so you can compare or restore any earlier snapshot. For research use only.
Screenshots
How to use
- 1Add it in ChatGPT
Open Plasmole in ChatGPT's Plugin directory (button above), select + to add it and sign in if asked.
- 2Use it in a chat
Type @ in the composer and pick Plasmole, or start your message with its name. ChatGPT may also suggest it when it fits what you ask.
Things to ask
- “Show me the pBR322 map with its genes and restriction sites (accession J01749).”
- “Fetch the pUC19 cloning vector (M77789.2) from NCBI and show me an annotated plasmid map.”