Use Boltz from Codex for biomolecular modeling workflows: predict structure and binding for protein, RNA, DNA, and ligand complexes; rank small-molecule or protein libraries against targets; and design novel small molecules, peptides, antibodies, nanobodies, or custom protein binders with structures and confidence metrics.
Install
- 1Add it in ChatGPT
Open Plugins in the ChatGPT sidebar (web or desktop), search for “Boltz” and select +. You'll be asked to sign in to any connected service on first use. Then type @ in a chat to call it.
Skills 8
- Boltz Check Status
Inspect Boltz jobs and recover outputs
- Boltz CLI Setup
Install, update, verify, and authenticate boltz-api
- Boltz Protein Design
Design peptide or antibody binders
- Boltz Protein Screen
Screen protein binders against a target
- Boltz Small Molecule ADME
Predict ADME (solubility, permeability, logD) from SMILES
- Boltz Small Molecule Design
Design novel ligands for a protein target
- Boltz Small Molecule Screen
Screen SMILES libraries against protein targets
- Boltz Structure and Binding
Predict complexes and score Boltz binding jobs
Things to ask
- “Predict EGFR L858R binding to osimertinib”
- “Design nanobodies for a SARS-CoV-2 RBD epitope”
- “Design selective JAK2 binders from Enamine REAL”